In the paper a method was proposed which enabled several Cr, Tm, Ho∶YAG lasersworking in a controlled sequence. High average power Cr, Tm, Ho∶YAG laserswere obtained and coupled into a low OH- quartz fiber with a core diameter of 320μm. The output power could meet various requirements in different app lications. For the threeroute Cr, Tm, Ho∶YAG lasers, the output powerwas 50. 17W under the condition of single pulse input energy of 100J and repetition rate of 30Hz. After the fiber coup ling, the output powerwas 35. 65W with a coup ling efficiency of 71%.