The calibration technology on the Optoelectronic system with visible,laser,and rotational mechanical axis is discussed in this paper,this is the calibration of multispectral spatial rotation optical axis,the characteristics is not only the parallelism adjustment of optical axis where relative rotational movement occurs,but also the danger of invisible high-energy laser.The reason and error resulted from the multibeam axis spatial rotation are summarized,proposing the adjustment technique with both safety and convenience.It begins that the harmful invisible laser is simulated by the visible light camera.Then,the special rotative adjustment pedestal and the reference source are designed and processed,and the error of the different spatial relative position between camera axis and visual axis is measured by turning the rotative pedestal and adjusted utilizing dual-optical wedge technique.Finally,the axis of laser and telescope in the discretional azimuth is kept parallel based on the consistence of precision in laser axis relative to fitting surface and camera through the transition frock,the error is limited to be less than 0.1mrad.