To study the flash blindness of laser to rabbit eyes and monkey eyes under the condition of different distances(Light Spot) and background light intensity by rhesus monkeys and pigmented rabbits. The visual electrophysiologic recording system was adopted to monitor the flash blindness. Meanwhile, to adopt fundus camera observed the post-exposured retinal. The recovery time of wave b prolonged as expose dose increased and shortened as background light intensity enhanced. Flash blindness will not lead to the retinal lesions.