To overcome the problem of ghosting artifacts and parameters drifting over time in current IR scene，a non uniformity correction algorithm via midway equalization histogram is presented. Firstly the idea of scene correction is used to the image columns，and then the midway equalization histogram of the column is computed to take the place of original cumulative histogram. Experimental results show that the proposed algorithm is superior to the total variation algorithm and has advantages of simpler，faster and easier to engineering application.