The technology of laser protection using the phase transition properties of vanadium oxide has become a research focus.Vanadium oxide thin film was fabricated on ordinary glass substrates by direct current (DC) magnetron sputtering from a vanadium metal target and subsequent annealing.The phase transition of the film was observed by measuring its resistance-temperature (R-T) characteristic curve.Continuous CO2 laser with a power of 8.9 W and a spot diameter of 4.4 mm was used to irradiate on both bare glass disc and glass disc covered with vanadium oxide film to do damage experiments.The data indicated that the film had a semiconductor-metal phase transition temperature of about 30 °C，the bidirectional reflectance of the film before and after the phase transition were 13.48% and 76.4% respectively,and the bare glass disc broke down after irradiated for 7.5 s while the glass disc with vanadium oxide film remained unbroken for 38 s.This results show that the fabricated sample has the ability of laser protection because of its high reflectance after the phase transition.