For the traditional femtosecond laser-assisted lens fragmentation surgery,it was necessary to select different scanning solutions according to the lens opacity of the cataract patients,and the scanning path of each layer was discontinuous. In view of this problem,a parametric helical laser scanning lens fragmentation path was proposed. Firstly,the parameterized definition of the helical scanning path was given. Then,the mathematical model of the scanning path was solved and the coordinate values of the key data points in the path were solved. Finally,the simulation model of the scanning path was established,and the correctness of the mathematical model of the scanning path was verified. Simulation results show that each layer path of this lens fragmentation solution is continuous,and different cutting effects can be achieved by changing the corresponding parameters. It provides a new type of lens fragmentation solution for femtosecond laser-assisted cataract surgery,and has a certain practical value.