In order to meet the requirement of high voltage,high stability,accuracy and easy control driving voltage for photoelastic modulator,a high voltage driving circuit based on FPGA control and full bridge LC resonant boost is designed.Compared with the traditional photoelastic modulator driving control circuit,it reduces the DC power supply input voltage,controls the photoelastic modulator frequency through DDS square wave frequency,and adjusts square wave duty cycle to control the value of output voltage.The results of photoelastic modulator experiment show that the square wave duty cycle range of 0~50% corresponding to peak voltage can be adjusted in the range of 0~840 V at the resonant frequency of the photoelastic modulator when external DC voltage is 5 V.The circuit has the advantages of reliable,easy control,heavy load capacity,and it can realize the real-time and accurate control of the driving voltage of photoelastic modulator.