The different structures of aircraft have different effects on the fatigue life under laser shock peening.Based on the ABAQUS simulation,the residual stress distribution after laser peening on hole 2.6,fillet R3 and round bar(Min- diameter 20)with different power density is analyzed.The laser peening and tensile fatigue tests were performed on the corresponding TC4-DT titanium alloy specimens.The results show the fatigue gain of fillets and corners are larger at Max-stress 385 MPa and stress ratio R=0.1.The fatigue gain of fillet is 238.4 % at 12.75 GW/cm2,and hole′s fatigue gain is 243.3 % at 22.67 GW/cm2.The fatigue gain of the bar is negative(the gain is reduced to -94.1 % at 22.67 GW/cm2).The laser shock peening fillet and hole greatly improve the fatigue life of its weak region,which makes the fatigue gain more of the structure.Laser shock peening on the rotating body under tensile load may have a large negative impact,and the results have guiding significance for laser shock enhancement of characteristic structure.