The function of the pixel ADC is to convert the current signal of the infrared detector into a digital signal at the pixel level.This paper designs a pixel ADC that can realize non-uniformity correction and blind element compensation,which avoids the way of performing at the algorithm level,reduces the difficulty of image processing algorithms,and reduces the resources consumed by the image processing algorithms.The proposed pixel ADC is based on the 64×64 detector array to design the infrared focal plane readout circuit which is taped out on 40 nm CMOS Process.The area of pixel ADC is less than 30μm×30μm,and the area of readout circuit is about 4.5mm×4.5mm.The pixel ADC is proved that the realization of non-uniformity correction and blind element compensation.The non-uniformity correction range can reach 34%.