The working principle of laser cleaning paint layer was analyzed based on the research data. The finite element simulation model of pulsed laser cleaning epoxy zinc yellow paint layer on 5052 aluminum alloy surface was established by Ansys,and the influence of different scanning velocity on the temperature field and stress field of laser cleaning paint layer was analyzed when the laser power was 20 W.Of 5052 aluminum alloy surface lacquer layer from stress were determined and the simulation results were validated,the experiments show that when the scanning speed is 1200mm/s,the temperature field and stress field produced by the laser cleaning lacquer layer have the best removal effect. While,when the scanning speed is 200 ～ 1000mm/s,the plasma shielding effect results in the decrease of the absorption rate of laser. The experimental results verified the correctness of the simulation model,when in high-speed scanning and the influence of plasma shielding is not significant. The model can provide selection and effect prediction for the technological parameters of laser cleaning lacquer layer.