Aiming at the problems of obvious color bias and fuzzy detail information in infrared long wave dual band pseudo color fusion image,this paper summarizes the advantages and disadvantages of typical traditional color fusion algorithm,proposes the idea of dividing Difference Region Fuse(DRF),and adds iterative normalized image processing in the image preprocessing.Combined with the characteristics of medium and long wave difference,YCbCr color space is introduced,and 16bit original infrared image is used to perform color fusion directly.Simulation results show that the proposed DRF algorithm has a remarkable fusion effect.